A Novel Approach to Develop Age-equivalent Models for Pediatric Long Bones

Principal Investigator: Sriram Balasubramanian, PhD, Children's Hospital of Philadelphia

The objective of this study is to develop and characterize an age-equivalent animal model based on regional dual-energy X-ray absorptiometry (DXA) and Peripheral Quantitative Computed Tomography (pQCT) parameters leveraged from ongoing research at CHOP measuring these parameters on a large sample of real children.